Product Description

Buy Zapain 30mg 500mg

Buy Zapain 30mg 500mg . What Zapain Capsules are and what they are used for
This medicine has been prescribed for you for the relief of severe pain. Zapain Capsules contain
paracetamol and codeine. It contains codeine. Codeine belongs to a class of medicines called
opioid, which are ‘pain relievers. It also contains Paracetamol which is an analgesic (relieves pain)
and an antipyretic (lowers raised temperatures). Zapain Capsules can be used in children over 12
years of age for the short-term relief of moderate pain that is not relieved by other painkillers such
as paracetamol or ibuprofen alone.
This medicine has been prescribed to you and should not be given to anyone else.
Opioids can cause addiction and you may get withdrawal symptoms if you stop taking it suddenly.
Your prescriber should have explained how long you will be taking it for and when it is appropriate
to stop, how to do this safely.

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2. What you need to know before you take Zapain Capsules
Zapain Capsules should not be taken longer than as directed by your doctor. Taking codeine (an
active ingredient of Zapain Capsules) regularly for a long time can lead to addiction, which might
cause you to feel restless and irritable when you stop the capsules.
If a pain killer is used too long for headaches, it can make them worse. Do not take Zapain Capsules if
• you are allergic to paracetamol or codeine, or any of the other ingredients of this medicine (listed
in section 6

• you suffer from severe kidney or liver disease
• you know that you metabolise very rapidly codeine into morphine

emphysema
Do not use Zapain Capsules for pain relief in children and adolescents (0-18 years of age) after
removal of their tonsils or adenoids as Codeine in Zapain Capsules may cause obstructive sleep
apnoea syndrome (sleep disruption due to respiratory pauses).
Zapain Capsules should not be taken by children under 12 years of age.
Warnings and precautions
Talk to your doctor or pharmacist before taking Zapain Capsules if:

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• you have kidney or liver problems, because the dose might need to be lower
• you have myasthenia gravis (muscle weakness, weakness of facial muscles including the eye
muscles and difficulty in swallowing)

• you are suffering from decreased brain activity
• you are suffering from inflammation or obstruction of bowel
which urine is passed) • you are taking monoamine oxidase inhibitors (MAOIs) or have been taking them within the last
two weeks. MAOIs such as phenelzine, moclobemide or isocarboxazid are medicines used to treat
depression
Talk to your prescriber before taking this medicine if you:
• are or have ever been addicted to opioids, alcohol, prescription medicines, or illegal drugs.
• have previously suffered from withdrawal symptoms such as agitation, anxiety, shaking or
sweating, when you have stopped taking alcohol or drugs.
• feel you need to take more of Zapain Capsules to get the same level of pain relief, this may mean
you are becoming tolerant to the effects of this medicine or are becoming addicted to it. Speak to
your prescriber who will discuss your treatment and may change your dose or switch you to an
alternative pain reliever.

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Taking this medicine regularly, particularly for a long time, can lead to addiction. Your prescriber
should have explained how long you will be taking it for and when it is appropriate to stop, how to
do this safely.
Rarely, increasing the dose of this medicine can make you more sensitive to pain. If this happens,
you need to speak to your prescriber about your treatment.
Addiction can cause withdrawal symptoms when you stop taking this medicine. Withdrawal
symptoms can include restlessness, difficulty sleeping, irritability, agitation, anxiety, feeling your
heartbeat (palpitations), increased blood pressure, feeling or being sick, diarrhoea, loss of appetite,
shaking, shivering or sweating. Your prescriber will discuss with you how to gradually reduce your
dose before stopping the medicine. It is important that you do not stop taking the medicine suddenly
as you will be more likely to experience withdrawal symptoms. Opioids should only be used by those they are prescribed for. Do not give your medicine to anyone
else.Buy Zapain 30mg 500mg
Taking higher doses or more frequent doses of opioid, may increase the risk of addiction. Overuse
and misuse can lead to overdose and/or death.
Codeine is transformed to morphine in the liver by an enzyme. Morphine is the substance that
produces pain relief. Some people have a variation of this enzyme and this can affect people in
different ways. In some people, morphine is not produced or produced in very small quantities and
it will not provide enough pain relief. Other people are more likely to get serious side effects
because a very high amount of morphine is produced. If you notice any of the following side
effects, you must stop taking this medicine and seek immediate medical advice: slow or shallow
breathing, confusion, sleepiness, small pupils, feeling or being sick, constipation, lack of appetite.
Children and adolescents Buy Zapain 30mg 500mg
Use in children and adolescents after surgery
Codeine should not be used for pain relief in children and adolescents after removal of their tonsils
or adenoids due to Obstructive Sleep Apnoea Syndrome (sleep disruption due to respiratory
pauses).

• Buy Zapain 30mg/500mg Tabletes is a pain relief medication that contains both paracetamol and codeine
• Zapain is sometimes prescribed when milder forms of pain relief such as standalone paracetamol or ibuprofen have not relieved the pain
• The generic version of Zapain is called co-codamol.
• Zapain is only available on prescription from a doctor, nurse or pharmacist prescriber
• Common indications for Zapain prescription include toothache, migraine and aching joints associated with arthritis
• The codeine in Zapain can become addictive when it is used long term, so you will be advised that Zapain is likely to be a short term medication to avoid dependence
• It is important to read the patient leaflet for a full list of side effects and cautions.

How Does Zapain Work?

Zapain contains a combination of paracetamol and codeine.

Paracetamol has been used for over 100 years, but its mechanism of action is still unclear. It is likely that paracetamol reduces prostaglandin production in the brain, which in turn increases our tolerance to pain. This means that although the pain might still be there, we feel less bothered by it.

Codeine is part of the drug family called opioids. Opioids work by blocking pain signals in the brain and spinal cord, so that the pain subsides or completely disappears.

It is beneficial to take more than one type of pain relief medication when trying to manage moderate to severe pain. As Zapain combines two drugs in one tablet, it is favoured by many as it reduces the total number of pills you need to take.

Use in children with breathing problems
Codeine is not recommended in children with breathing problems, since the symptoms of morphine
toxicity may be worse in these children. Other medicines and Zapain Capsules
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other
medicines.
Some medicines interact with each other and this can alter their effect. It is particularly important to
tell your doctor or pharmacist if you are taking the following medicines:
• MAOIs used to treat depression, taken within the last 14 days (refer to “take special care” in
section 2 above)
• phenothiazines (medicines that calm your mood) or tricyclic antidepressants (e.g. amitriptyline)
• muscle relaxants (e.g. baclofen or diazepam)
cimetidine, colestyramine)
• aspirin, other painkillers and strong painkillers called opioids
• medicines which prevent blood clotting (anticoagulants such as warfarin)
Capsules. Some products which can be bought without a prescription may contain paracetamol or
codeine, so always check the labels for ingredients.

Zapain Capsules can interfere with some laboratory tests used for determining some diseases. Concomitant use of Zapain Capsules and sedative medicines such as benzodiazepines or related
drugs increases the risk of drowsiness, difficulties in breathing (respiratory depression), coma and may be life-threatening. Because of this, concomitant use should only be considered when other
treatment options are not possible.
However if your doctor does prescribe Zapain Capsules together with sedative medicines the dose
and duration of concomitant treatment should be limited by your doctor.
Please tell your doctor about all sedative medicines you are taking and follow your doctor’s dose
recommendation closely. It could be helpful to inform friends or relatives to be aware of the signs
and symptoms stated above. Contact your doctor when experiencing such symptoms.
Zapain Capsules with food, drink and alcohol
Do not drink alcohol whilst taking Zapain Capsules. Swallow the capsules with a glass of water. Do
not bite or chew the capsules.
Pregnancy, breast-feeding and fertility
If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask
your doctor or pharmacist for advice before taking this medicine.Pregnancy
Do not take Zapain Capsules if you are pregnant or think you might be pregnant unless you have
discussed this with your prescriber and the benefits of treatment are considered to outweigh the
potential harm to the baby.
If you use Zapain Capsules during pregnancy, your baby may become dependent and experience
Breastfeeding
Do not take Zapain Capsules while you are breastfeeding as codeine passes into breast milk and will
affect your baby.
Driving and using machines
Zapain Capsules may cause dizziness or drowsiness and you should not drive or operate machinery
if you are affected this way. Codeine may disturb your vision.

The medicine can affect your ability to drive as it may make you sleepy or dizzy.
· do not drive while taking this medicine until you know how it affects you
 you have taken it according to the instructions given by the prescriber or in the information
provided with the medicine and
 it was not affecting your ability to drive safely.
Talk to your doctor or pharmacist if you are not sure whether it is safe for you to drive while taking
this medicine.

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Zapain Capsules contains sodium
This medicine contains less than 1 mmol sodium (23 mg) per dosage, that is to say essentially
‘sodium-free’. 3. How to take Zapain Capsules
Always take this medicine exactly as your doctor or pharmacist has told you. Check with your
doctor or pharmacist if you are not sure. Your prescriber should have discussed with you, how long the course of capsules will last. They
will arrange a plan for stopping treatment. This will outline how to gradually reduce the dose and
stop taking the medicine.
The recommended dose is one or two capsules every four to six hours as required up to a maximum
of 8 capsules in any 24 hour period.
If you feel the effect of Zapain Capsules is too strong or too weak or your symptoms persist, speak
to your doctor or pharmacist.
If the pain does not improve after 3 days,
talk to your doctor for advice.
Check with your
doctor about this.
Use in children and adolescents
Children aged 16-18 years: the recommended dose is one to two capsules every 6 hours when
necessary up to a maximum of 8 capsules in 24 hours.
Children aged 12 – 15 years: the recommended dose is one capsule every 6 hours when necessary
up to a maximum of 4 capsules in 24 hours.
breathing problems.
If you take more Zapain Capsules than you should
because of the risk of delayed, serious liver damage. If you forget to take Zapain Capsules
Do not take more than one dose at a time. If you forget to take a dose then take your next dose at the
usual time.Buy Zapain 30mg 500mg
Do not take a double dose to make up for a forgotten dose.
If you stop taking Zapain Capsules
Do not suddenly stop taking this medicine. If you want to stop taking this medicine, discuss this
with your prescriber first. They will tell you how to do this, usually by reducing the dose gradually
Withdrawal symptoms such as
restlessness, difficulty sleeping, irritability, agitation, anxiety, feeling your heartbeat (palpitations),
increased blood pressure, feeling or being sick, diarrhoea, shaking, shivering or sweating may occur
if you suddenly stop taking this medicine.
If you have any further questions on the use of this medicine, ask your doctor or pharmacist.
4. POSSIBLE SIDE EFFECTS
4. Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.
Stop taking the medicine and seek immediate medical advice if you notice the following:
All medicines can cause allergic reactions although serious allergic reactions are very rare. Any
sudden wheeziness, difficulty in breathing, swelling of the eyelids, face or lips, rash or itching Other possible side effects are:

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• light headedness, dizziness, sleepiness
• stomach pains, constipation.
Lying down may help these effects if they happen.
Other side effects include:Buy Zapain 30mg 500mg
Uncommon: may affect up to 1 in 100 people
• Drug Withdrawal
When you stop taking Zapain Capsules, you may experience drug withdrawal symptoms, which
include restlessness, difficulty sleeping, irritability, agitation, anxiety, feeling your heartbeat
(palpitations), increased blood pressure, feeling or being sick, diarrhoea, shaking, shivering or
sweating.
• hearing loss
pancreas(pancreatitis)
• changes in blood cells, such as low number of cells which fight infection and of cells which are
involved in blood clotting resulting in tiredness, bruising easily.
If you notice any of the following signs whilst taking Zapain Capsules, it could be a sign that you
have become addicted.
– When you stop taking the medicine you feel unwell, and you feel better once taking the medicine
again.
If you notice any of these signs, it is important you talk to your prescriber.
hearing loss.
Prolonged use of a pain killer for headaches can make them worse.
If any of the side effects become serious, or if you notice any side effect not listed in this leaflet,
please tell your doctor or pharmacist. Reporting of side effects
If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side
effects not listed in this leaflet. You can also report side effects directly via the Yellow Card
Scheme website: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google
Play or Apple App Store. By reporting side effects you can help provide more information on the
safety of this medicine.

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5. HOW TO STORE ZAPAINCAPSULES
5. How to store Zapain Capsules
Keep out of the reach and sight of children.
Keep this medicine in a dry place.
Do not store above 25°C.
Protect from light.Buy Zapain 30mg 500mg
Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to
throw away medicines you no longer use. These measures will help to protect the environment.
6. FURTHER INFORMATION
6. Contents of the pack and other information
What Zapain Capsules contain
• the active substances are Paracetamol, 500mg and Codeine Phosphate, 30mg
• the other ingredients are maize starch, sodium lauryl sulphate, talc, magnesium stearate,
croscarmellose sodium, gelatin, titanium dioxide E171, erythrosine E127 and red iron oxide E172.
What Zapain Capsules look like and contents of the pack
Zapain Capsules are available in aluminium blister packs or plastic containers with child resistant
lids of 50, 56, 100 or 112 capsules. Marketing Authorisation Holder
Mercury Pharmaceuticals Ltd.,
Capital House, 85 King William Street, London EC4N 7BL, UK
Manufactured By
Bristol Laboratories Ltd, Laporte Way, Luton, Bedfordshire, LU4 8WL, UK

Additional Information